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Article

Structural perspectives on HCV humoral immune evasion mechanisms.

Current opinion in virology - 1 Aug 2021

Sevvana Madhumati, Keck Zhenyong, Foung Steven Kh, Kuhn Richard J

Abstract excerpt

The molecular mechanisms of hepatitis C virus (HCV) persistence and pathogenesis are poorly understood. The design of an effective HCV vaccine is challenging despite a robust humoral immune response against closely related strains of HCV. This is primarily because of the huge genetic diversity of HCV and the molecular evolution of various virus escape mechanisms. These mechanisms are steered by the presence of a...

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Share to Antibodies, Neutralizing
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Share to Hepatitis C Antibodies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immune Evasion

Share to Immunity, Humoral

Share to Immunodominant Epitopes

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Share to Viral Envelope Proteins

Source

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Identifiers

PMID: 34091143
DOI: 10.1016/j.coviro.2021.05.002
PMCID: PMC8319080

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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