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Article

Possible association of cytotoxic T lymphocyte antigen-4 genetic polymorphism with liver damage of primary biliary cirrhosis in Japan.

Fukushima journal of medical science - 1 Dec 2006

Kanno Yukiko, Rai Tsuyoshi, Monoe Kyoko, Saito Hironobu, Takahashi Atsushi, Irisawa Atsushi, Ohira Hiromasa

Abstract excerpt

Cytotoxic T lymphocyte antigen-4 (CTLA-4) is an important inhibitor of T-lymphocyte response. Polymorphisms in the CTLA-4 gene have been reported to be associated with numerous autoimmune diseases. The aim of this study was to determine whether polymorphisms of CTLA-4 exon 1 (+49) genes are assoc...

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Source

Identifiers

PMID: 17427759
DOI: 10.5387/fms.52.79

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17427759-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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