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Article

The Ancient Genetic Networks of Obesity: Whole-Animal Automated Screening for Conserved Fat Regulators.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018

Ke Wenfan, Drangowska-Way Anna, Katz Daniel, Siller Karsten, O'Rourke Eyleen J

Abstract excerpt

Caenorhabditis elegans is the first and only metazoan model that enables whole-body gene knockdown by simply feeding their standard laboratory diet, E. coli, carrying RNA interference (RNAi)-expressing constructs. The simplicity of the RNAi treatment, small size, and fast reproduction rate of C. elegans allow us to perform whole-animal high-throughput genetic screens in wild-type, mutant, or otherwise genetically...

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Identifiers

PMID: 29736715
DOI: 10.1007/978-1-4939-7847-2_10
PMCID: PMC8252661

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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