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Article

Impact of polymorphisms in genes involved in autoimmune disease on inhibitor development in Chinese patients with haemophilia A.

Thrombosis and haemostasis - 1 Jan 2012

Lu Yeling, Ding Qiulan, Dai Jing, Wang Hongli, Wang Xuefeng

Abstract excerpt

One of the most severe and important complication in the treatment of haemophilia A (HA) patients is the formation of inhibitors. The mechanism that leads to factor (F)VIII inhibitor formation is complicated. Both genetic and environmental factors have been mentioned to play decisive roles. Recently, polymorphisms in the genes encoding interleukin-10 (IL-10), tumour necrosis factor-alpha (TNF-α), cytotoxic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22116520
DOI: 10.1160/TH11-06-0425

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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