Article
[Relationship between factor VIII inhibitor development and polymorphisms of TNFα and CTLA-4 gene in Chinese Han patients with hemophilia A].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Mar 2011
Zhang Lu-lu, Yu Zi-qiang, Zhang Wei, Cao Li-juan, Su Jian, Bai Xia, Ruan Chang-geng
Abstract excerpt
OBJECTIVE: To investigate the potential association between factor VIII inhibitor development and polymorphisms of tumor necrosis factor-α (TNF-α)-308 and cytotoxic T-lymphocyte associated protein-4 gene in Chinese Han patients with hemophilia A (HA). METHODS: The single base change polymorphism in TNF-α and CTLA-4 gene was analyzed in 140 Chinese Han patients with hemophilia A who have been treated with...
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