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Article

Serum TNF-α Level as a Possible Predictor of Inhibitor Levels in Severe Hemophilia A.

BioMed research international - 1 Jan 2021

Susanah Susi, Raspati Harry, Sari Nur Melani, Rakhmilla Lulu Eva, Sribudiani Yunia, Moestopo Octawyana, Sinaga Puspasari, Idjradinata Ponpon, Maskoen Ani Melani

Abstract excerpt

BACKGROUND: The development of factor VIII (FVIII) inhibitor in patients with hemophilia A (PWHA) is a great challenge for hemophilia care. Both genetic and environmental factors led to complications in PWHA. The development of inhibitory antibodies is usually induced by the immune response. Tumor necrosis factor α (TNF-α), one of the cytokines, might contribute to its polymorphism. In this study, we investigated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34778454
DOI: 10.1155/2021/6483490
PMCID: PMC8589501

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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