Article
Understanding inhibitor development in haemophilia A: towards clinical prediction and prevention strategies.
Haemophilia : the official journal of the World Federation of Hemophilia - 1 Jan 2010
Coppola A, Santoro C, Tagliaferri A, Franchini M, DI Minno G
Abstract excerpt
Inhibitor development, because of its impact on patients' morbidity and quality of life, is presently the most serious complication of haemophilia A treatment. The identification of several genetic and non-genetic risk factors may be used for the stratification of inhibitor risk and the definition of prevention strategies, particularly for patients with a high-risk genetic profile. The most extensively studied...
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