Article
The Development of FVIII Inhibitors in Relation to IL10 Gene Polymorphism in Hemophilia A Egyptian Pediatric Patients.
Fetal and pediatric pathology - 1 Jun 2017
Sadek Hoda, Youssry Ilham, Ibrahim Nihal Salah Eldeen, Abou-Elalla Amany Ahmed, Atef Gehad, Mousa Somaia Mohammed
Abstract excerpt
BACKGROUND: Development of inhibitors against Factor VIII (FVIII) in hemophilia A patients is a serious complication of therapy. Many cytokines, including interleukin-10 (IL10), may affect inhibitor development; however, literature data are not sufficient to prove this association. The aim of this study was to investigate the relation between FVIII inhibitor formation and IL10-1082A/G polymorphism among Egyptian...
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