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Article

Secretion in yeast of mutant human lysozymes with and without glutathione bound to cysteine 95.

The Journal of biological chemistry - 5 Oct 1990

Taniyama Y, Seko C, Kikuchi M

Abstract excerpt

A mutant human lysozyme C77A, in which Cys-77 is replaced with Ala, was secreted by Saccharomyces cerevisiae as two proteins (C77A-a and C77A-b) with different specific activities. A peptide fragment from Val93 to Ala108 was obtained from C77A-a by pepsin digestion, and examined by fast atom bombardment mass spectrometry and amino acid analysis. The results showed that glutathione was attached to the thiol group...

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PMID: 2211592

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Secretion in yeast of mutant human lysozymes with and without glutathione bound to cysteine 95.PMID 2211592Read ↗

Folding mechanism of mutant human lysozyme C77/95A with increased secretion efficiency in yeast.Semantic proximity Read ↗

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The crystal structure of a mutant human lysozyme C77/95A with increased secretion efficiency in yeast.Semantic proximity Read ↗

Accelerated secretion of human lysozyme with a disulfide bond mutation.Semantic proximity Read ↗

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