Article

ExGRS: exome-wide genetic risk score to predict high myopia across multi-ancestry populations

2024-06-04

Abstract excerpt

<title>Abstract</title> <p>High myopia (HM), characterized by severe myopic refractive error, stands as a leading cause to visual impairment and blindness globally. HM is a multifactorial ocular disease and presents high heterogeneity in genetics. Employing a genetic risk score (GRS) is useful for capturing genetic susceptibility to HM. Incorporating rare variations into GRS assessment, though presents methodolog...

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Literature Corpus work: adc6e847-4d9a-55c2-b40e-26878a5d20dc
DOI: 10.21203/rs.3.rs-4188555/v1

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