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Article

When do myopia genes have their effect? Comparison of genetic risks between children and adults.

Genetic epidemiology - 1 Dec 2016

Tideman J Willem L, Fan Qiao, Polling Jan Roelof, Guo Xiaobo, Yazar Seyhan, Khawaja Anthony, Höhn René, Lu Yi, Jaddoe Vincent W V, Yamashiro Kenji, Yoshikawa Munemitsu, Gerhold-Ay Aslihan, Nickels Stefan, Zeller Tanja, He Mingguang, Boutin Thibaud, Bencic Goran, Vitart Veronique, Mackey David A, Foster Paul J, MacGregor Stuart, Williams Cathy, Saw Seang Mei, Guggenheim Jeremy A, Klaver Caroline C W

Abstract excerpt

Previous studies have identified many genetic loci for refractive error and myopia. We aimed to investigate the effect of these loci on ocular biometry as a function of age in children, adolescents, and adults. The study population consisted of three age groups identified from the international CREAM consortium: 5,490 individuals aged <10 years; 5,000 aged 10-25 years; and 16,274 aged >25 years. All participants...

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Identifiers

PMID: 27611182
DOI: 10.1002/gepi.21999

Genes

GJD2
BMP2
CHRNG
KCNQ5
LAMA2
ZIC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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