Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Education interacts with genetic variants near GJD2, RBFOX1, LAMA2, KCNQ5 and LRRC4C to confer susceptibility to myopia.

PLoS genetics - 1 Nov 2022

Clark Rosie, Pozarickij Alfred, Hysi Pirro G, Ohno-Matsui Kyoko, Williams Cathy, Guggenheim Jeremy A

Abstract excerpt

Myopia most often develops during school age, with the highest incidence in countries with intensive education systems. Interactions between genetic variants and educational exposure are hypothesized to confer susceptibility to myopia, but few such interactions have been identified. Here, we aimed to identify genetic variants that interact with education level to confer susceptibility to myopia. Two groups of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Alleles
Share to Educational Status

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Myopia

Share to Refractive Errors

Share to RNA Splicing Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 36395078
DOI: 10.1371/journal.pgen.1010478
PMCID: PMC9671369

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Education interacts with genetic variants near GJD2, RBFOX1, LAMA2, KCNQ5 and LRRC4C to confer susceptibility to myopia.PMID 36395078Read ↗

Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error.Semantic proximity Read ↗

Assessing the Genetic Predisposition of Education on Myopia: A Mendelian Randomization Study.Semantic proximity Read ↗

IMI-Myopia Genetics Report.Semantic proximity Read ↗

Gene-environment Interaction in Spherical Equivalent and Myopia: An Evidence-based Review.Semantic proximity Read ↗

Education and myopia: assessing the direction of causality by mendelian randomisationSemantic proximity Read ↗

Meta-analysis of 542,934 subjects of European ancestry identifies new genes and mechanisms predisposing to refractive error and myopia.Semantic proximity Read ↗

Multi-ancestry genome-wide association analyses of refractive error augment genetic discovery and polygenic prediction.Semantic proximity Read ↗

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.Semantic proximity Read ↗

IMI – Myopia Genetics ReportSemantic proximity Read ↗

Myopia and level of education: results from the Gutenberg Health Study.Semantic proximity Read ↗

Childhood gene-environment interactions and age-dependent effects of genetic variants associated with refractive error and myopia: The CREAM Consortium.Semantic proximity Read ↗

Update on the epidemiology and genetics of myopic refractive errorSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.