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Article

The Roles of PAX6 and SOX2 in Myopia: lessons from the 1958 British Birth Cohort.

Investigative ophthalmology & visual science - 1 Oct 2007

Simpson Claire L, Hysi Pirro, Bhattacharya Shomi S, Hammond Chris J, Webster Andrew, Peckham Catherine S, Sham Pak C, Rahi Jugnoo S

Abstract excerpt

PURPOSE: Myopia is a common complex trait that affects up to 60% of some populations. Its development is influenced by multiple genes and environmental factors. PAX6 and SOX2 are genes with fundamental roles in ocular growth and development, and they have been linked with myopia in a recent linka...

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Source

Identifiers

PMID: 17898260
DOI: 10.1167/iovs.07-0231

Genes

PAX6
SOX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17898260-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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