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Article

Regulatory roles for APJ, a seven-transmembrane receptor related to angiotensin-type 1 receptor in blood pressure in vivo.

The Journal of biological chemistry - 18 Jun 2004

Ishida Junji, Hashimoto Tatsuo, Hashimoto Yasumi, Nishiwaki Shiro, Iguchi Taku, Harada Shuichi, Sugaya Takeshi, Matsuzaki Hitomi, Yamamoto Rie, Shiota Naotaka, Okunishi Hideki, Kihara Minoru, Umemura Satoshi, Sugiyama Fumihiro, Yagami Ken-Ichi, Kasuya Yoshitoshi, Mochizuki Naoki, Fukamizu Akiyoshi

Abstract excerpt

APJ is a G-protein-coupled receptor with seven transmembrane domains, and its endogenous ligand, apelin, was identified recently. They are highly expressed in the cardiovascular system, suggesting that APJ is important in the regulation of blood pressure. To investigate the physiological function...

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Source

Identifiers

PMID: 15087458
DOI: 10.1074/jbc.M404149200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15087458-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Regulatory roles for APJ, a seven-transmembrane receptor related to angiotensin-type 1 receptor in blood pressure in vivo.PMID 15087458Read ↗

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