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Article

Nef surfaces: where to interfere with function.

Current HIV research - 1 Oct 2011

Lulf Sebastian, Horenkamp Florian A, Breuer Sebastian, Geyer Matthias

Abstract excerpt

The HIV-1 Nef protein is an accessory protein of 24-27 kDa mass that mediates a multitude of effector functions in infected cells. Although not essentially required for viral replication, HIV-1 Nef exhibits stimulating potential towards disease progression to AIDS and is therefore considered a pathogenic factor in retroviridae. Here we correlate sequence conservation in HIV-1 Nef with surface hydrophobicity and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to nef Gene Products, Human Immunodeficiency Virus

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Source

Identifiers

PMID: 22103838
DOI: 10.2174/157016211798842053

Genes

PAK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence.

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Nef surfaces: where to interfere with function.PMID 22103838Read ↗

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