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Article

Region-specific deletions of RIM1 reproduce a subset of global RIM1α(-/-) phenotypes.

Genes, brain, and behavior - 1 Mar 2012

Haws M E, Kaeser P S, Jarvis D L, Südhof T C, Powell C M

Abstract excerpt

The presynaptic protein RIM1α mediates multiple forms of presynaptic plasticity at both excitatory and inhibitory synapses. Previous studies of mice lacking RIM1α (RIM1α(-/-) throughout the brain showed that deletion of RIM1α results in multiple behavioral abnormalities. In an effort to begin to delineate the brain regions in which RIM1 deletion mediates these abnormal behaviors, we used conditional (floxed)...

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Source

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Identifiers

PMID: 22103334
DOI: 10.1111/j.1601-183X.2011.00755.x
PMCID: PMC3268893

Genes

CA3
POMC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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