Article
An intermediate level of BMP signaling directly specifies cranial neural crest progenitor cells in zebrafish.
PloS one - 1 Jan 2011
Schumacher Jennifer A, Hashiguchi Megumi, Nguyen Vu H, Mullins Mary C
Abstract excerpt
The specification of the neural crest progenitor cell (NCPC) population in the early vertebrate embryo requires an elaborate network of signaling pathways, one of which is the Bone Morphogenetic Protein (BMP) pathway. Based on alterations in neural crest gene expression in zebrafish BMP pathway component mutants, we previously proposed a model in which the gastrula BMP morphogen gradient establishes an...
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