Article

Timing and Graded BMP Signalling Determines Fate of Neural Crest and Ectodermal Placode Derivatives from Pluripotent Stem Cells

2024-09-12

Abstract excerpt

Pluripotent stem cells (PSCs) hold many potential research and clinical benefits due to their ability to differentiate into nearly every cell type in the body. They are often used as model systems for early stages of ontogenesis to better understand key developmental pathways, and for drug screening. However, in order to fully realise the potential of PSCs and their translational applications, a deeper understandi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2744bd48-c3aa-5445-8a67-fe3c427333e1
DOI: 10.20944/preprints202409.0914.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Timing and Graded BMP Signalling Determines Fate of Neural Crest and Ectodermal Placode Derivatives from Pluripotent Stem CellsDOI 10.20944/preprints202409.0914.v1Read

Bone Morphogenetic Protein (BMP) signaling in development and human diseasesSemantic proximity Read

dlx3b/4b are required for the formation of the preplacodal region and otic placode through local modulation of BMP activity.Semantic proximity Read

Bmps: multifunctional regulators of mammalian embryonic development.Semantic proximity Read

Integrated Genetic Networks and Epigenetic Regulation in Tooth Development and MaturationSemantic proximity Read

Role and mechanism of BMP4 in bone, craniofacial, and tooth developmentSemantic proximity Read

Bone and cartilage differentiation.Semantic proximity Read

BMPs: From bone morphogenetic proteins to body morphogenetic proteinsSemantic proximity Read

Relationship between neural crest cell specification and rare ocular diseases.Semantic proximity Read

BMP signaling in development and diseases: a pharmacological perspective.Semantic proximity Read

Differential BMP signaling controls formation and differentiation of multipotent preplacodal ectoderm progenitors from human embryonic stem cellsSemantic proximity Read

Top-Down Inhibition of BMP Signaling Enables Robust Induction of hPSCs Into Neural Crest in Fully Defined, Xeno-free ConditionsSemantic proximity Read

Bone morphogenetic proteins: an unconventional approach to isolation of first mammalian morphogens.Semantic proximity Read