Article
Calcineurin signaling regulates neural induction through antagonizing the BMP pathway.
Neuron - 2 Apr 2014
Cho Ahryon, Tang Yitai, Davila Jonathan, Deng Suhua, Chen Lei, Miller Erik, Wernig Marius, Graef Isabella A
Abstract excerpt
Development of the nervous system begins with neural induction, which is controlled by complex signaling networks functioning in concert with one another. Fine-tuning of the bone morphogenetic protein (BMP) pathway is essential for neural induction in the developing embryo. However, the molecular mechanisms by which cells integrate the signaling pathways that contribute to neural induction have remained unclear....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.