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Article

Bmp2 is required for cephalic neural tube closure in the mouse.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jan 2009

Castranio Trisha, Mishina Yuji

Abstract excerpt

BMPs have been shown to play a role in neural tube development particularly as dorsalizing factors. To explore the possibility that BMP2 could play a role in the developing neural tube (NT) beyond the lethality of Bmp2 null embryos, we created Bmp2 chimeras from Bmp2 null ES cells and WT blastocysts. Analysis of Bmp2 chimeras reveals NT defects at day 9.5 (E9.5). We found that exclusion of Bmp2 null ES cells from...

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Source

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Identifiers

PMID: 19097048
DOI: 10.1002/dvdy.21829
PMCID: PMC3086576

Genes

BMP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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