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Article

Mutation and crystallization of the first KH domain of human polycytosine-binding protein 1 (PCBP1) in complex with DNA.

Acta crystallographica. Section F, Structural biology and crystallization communications - 1 Oct 2011

Yoga Yano M K, Traore Daouda A K, Wilce Jacqueline A, Wilce Matthew C J

Abstract excerpt

Polycytosine-binding proteins (PCBPs) are triple KH-domain proteins that play an important role in the regulation of translation of eukaryotic mRNA. They are also utilized by viral RNA and have been shown to interact with ssDNA. Underlying their function is the specific recognition of C-rich nucleotides by their KH domains. However, the structural basis of this recognition is only partially understood. Here, the...

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Identifiers

PMID: 22102042
DOI: 10.1107/S1744309111028004
PMCID: PMC3212377

Genes

PCBP1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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