Phenotype suppression: a postulated molecular mechanism for mediating the relationship of proliferation and differentiation by Fos/Jun interactions at AP-1 sites in steroid responsive promoter elements of tissue-specific genes.

doi:10.1002/jcb.240450106

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Article

Phenotype suppression: a postulated molecular mechanism for mediating the relationship of proliferation and differentiation by Fos/Jun interactions at AP-1 sites in steroid responsive promoter elements of tissue-specific genes.

Journal of cellular biochemistry - 1 Jan 1991

Lian J B, Stein G S, Bortell R, Owen T A

Abstract excerpt

There is a generalized reciprocal relationship between cell growth and expression of genes that occurs following completion of proliferation, which supports the progressive development of cell and tissue phenotypes. Molecular mechanisms which couple the shutdown of proliferation with initiation o...

Topics

Animals
Base Sequence
Cell Differentiation
Cell Division
DNA-Binding Proteins
Humans
Molecular Sequence Data
Osteoblasts
Osteocalcin
Phenotype
Promoter Regions, Genetic
Protein-Tyrosine Kinases
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-fos

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Proto-Oncogene Proteins c-jun

Suppression, Genetic

Transcription Factors

Transcription, Genetic

Source

Open in PubMed

Identifiers

PMID: 1900844
DOI: 10.1002/jcb.240450106

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1900844-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.