Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Systemic inflammation in COPD: is genetic susceptibility a key factor?

COPD - 1 Mar 2006

Yanbaeva Dilyara G, Dentener Mieke A, Creutzberg Eva C, Wouters Emiel F M

Abstract excerpt

COPD is a multicomponent disease characterized by abnormal inflammatory response of the lungs to noxious particles that is accompanied by systemic effects like weight loss, muscle wasting, reduced functional capacity and impaired health status. A persistent low-grade systemic inflammatory response reflected by enhanced levels of acute phase proteins like C-reactive protein (CRP) and pro-inflammatory cytokines...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to C-Reactive Protein
Share to Inflammation
Share to Interleukin-6

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lymphotoxin-alpha

Share to Polymorphism, Genetic

Share to Pulmonary Disease, Chronic Obstructive

Share to Receptors, Tumor Necrosis Factor

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 17175665
DOI: 10.1080/15412550500493436

Genes

TNF
CRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Systemic inflammation in COPD: is genetic susceptibility a key factor?PMID 17175665Read ↗

Systemic inflammation, genetic susceptibility and lung function.Semantic proximity Read ↗

Smoking, Systemic Inflammation, and Airflow Limitation: A Mendelian Randomization Analysis of 98 085 Individuals From the General PopulationSemantic proximity Read ↗

The genetics of chronic obstructive pulmonary disease.Semantic proximity Read ↗

Immune-related gene polymorphisms in pulmonary diseases.Semantic proximity Read ↗

Identification of genetic variants in the TNF promoter associated with COPD secondary to tobacco smoking and its severity.Semantic proximity Read ↗

Genetic susceptibility.Semantic proximity Read ↗

Immune and genetic mechanisms in COPD: possible targets for therapeutic interventions.Semantic proximity Read ↗

Chronic Obstructive Pulmonary Disease, inflammation and co-morbidity--a common inflammatory phenotype?Semantic proximity Read ↗

Association between single-nucleotide polymorphism of cytokines genes and chronic obstructive pulmonary disease: A systematic review and meta-analysis.Semantic proximity Read ↗

Association of Cytokine Gene Polymorphisms in Patients with Chronic Obstructive Pulmonary DiseaseSemantic proximity Read ↗

Germline variants of the genes involved in NF-kB activation are associated with the risk of COPD and lung cancer development.Semantic proximity Read ↗

IL6 and CRP haplotypes are associated with COPD risk and systemic inflammation: a case-control study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.