Association of Cytokine Gene Polymorphisms in Patients with Chronic Obstructive Pulmonary Disease

Abstract excerpt

OBJECTIVE: Chronic obstructive pulmonary disease (COPD) is a major health problem. The disease is driven by abnormal inflammatory reactions in response to inhaled particles and fumes. Therefore, inflammatory mediators are postulated to be of distinct importance. Keeping in view of the above facts; we investigate the role of polymorphisms of cytokine genes in the genetic predisposition of COPD. METHODS: In this...

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