Article
IL6 and CRP haplotypes are associated with COPD risk and systemic inflammation: a case-control study.
BMC medical genetics - 9 Mar 2009
Yanbaeva Dilyara G, Dentener Mieke A, Spruit Martijn A, Houwing-Duistermaat Jeanine J, Kotz Daniel, Passos Valéria Lima, Wouters Emiel F M
Abstract excerpt
BACKGROUND: Elevated circulating levels of C-reactive protein (CRP), interleukin (IL)-6 and fibrinogen (FG) have been repeatedly associated with many adverse outcomes in patients with chronic obstructive pulmonary disease (COPD). To date, it remains unclear whether and to what extent systemic inflammation is primary or secondary in the pathogenesis of COPD. The aim of this study was to examine the association...
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