Article
Genes and abdominal aortic aneurysm.
Annals of vascular surgery - 1 Apr 2011
Hinterseher Irene, Tromp Gerard, Kuivaniemi Helena
Abstract excerpt
Abdominal aortic aneurysm (AAA) is a multifactorial disease with a strong genetic component. Since the first candidate gene studies were published 20 years ago, approximately 100 genetic association studies using single nucleotide polymorphisms (SNPs) in biologically relevant genes have been reported on AAA. These studies investigated SNPs in genes of the extracellular matrix, the cardiovascular system, the...
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