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Article

Effects of SLC10A2 variant rs9514089 on gallstone risk and serum cholesterol levels- meta-analysis of three independent cohorts.

BMC medical genetics - 17 Nov 2011

Tönjes Anke, Wittenburg Henning, Halbritter Jan, Renner Olga, Harsch Simone, Stange Eduard F, Lammert Frank, Stumvoll Michael, Kovacs Peter

Abstract excerpt

BACKGROUND: Recently, a single nucleotide polymorphism (SNP) rs9514089 in SLC10A2 (apical sodium-dependent bile acid transporter gene) has been identified as a susceptibility variant for cholelithiasis in humans. METHODS: Here we assessed the effects of rs9514089 on gallstone risk and related phenotypes of the metabolic syndrome in the self-contained population of Sorbs (183 cases with gallstones/826 controls)....

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Identifiers

PMID: 22093174
DOI: 10.1186/1471-2350-12-149
PMCID: PMC3261098

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