Article
Lipid trait-associated genetic variation is associated with gallstone disease in the diverse Third National Health and Nutrition Examination Survey (NHANES III).
BMC medical genetics - 21 Nov 2013
Goodloe Robert, Brown-Gentry Kristin, Gillani Niloufar B, Jin Hailing, Mayo Ping, Allen Melissa, McClellan Bob, Boston Jonathan, Sutcliffe Cara, Schnetz-Boutaud Nathalie, Dilks Holli H, Crawford Dana C
Abstract excerpt
BACKGROUND: Gallstone disease is one of the most common digestive disorders, affecting more than 30 million Americans. Previous twin studies suggest a heritability of 25% for gallstone formation. To date, one genome-wide association study (GWAS) has been performed in a population of European-descent. Several candidate gene studies have been performed in various populations, but most have been inconclusive. Given...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.