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Article

Obesity, Adiposity, and Risk of Symptomatic Gallstone Disease According to Genetic Susceptibility.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 May 2022

Lim Junghyun, Wirth Janine, Wu Kana, Giovannucci Edward, Kraft Peter, Turman Constance, Song Mingyang, Jovani Manol, Chan Andrew T, Joshi Amit D

Abstract excerpt

BACKGROUND & AIMS: Adiposity has been consistently associated with gallstone disease risk. We aimed to characterize associations of anthropometric measures (body mass index [BMI], recent weight change, long-term weight change, waist circumference, and waist-to-hip ratio) with symptomatic gallstone disease according to strata of gallstone disease polygenic risk score (PRS). METHODS: We conducted analysis among...

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Identifiers

PMID: 34217876
DOI: 10.1016/j.cgh.2021.06.044
PMCID: PMC8720320

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