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SLC10A1 rs2296651 variant (S267F mutation) predicts biochemical traits, hepatitis B virus infection susceptibility and the risk of gallstone disease.

Molecular genetics and genomics : MGG - 13 Jun 2024

Ko Yu-Lin, Tuan Wei-Lun, Teng Ming-Sheng, Su Wei-Chih, Wang Chia-Chi, Er Leay-Kiaw, Wu Semon, Hsu Lung-An

Abstract excerpt

Sodium taurocholate co-transporting polypeptide (NTCP), a bile acid transporter, plays a crucial role in regulating bile acid levels and influencing the risk of HBV infection. Genetic variations in the SLC10A1 gene, which encodes NTCP, affect these functions. However, the impact of SLC10A1 gene variants on the metabolic and biochemical traits remained unclear. We aimed to investigate the association of SLC10A1...

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PMID: 38869622
DOI: 10.1007/s00438-024-02153-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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