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Article

A variant of the SLC10A2 gene encoding the apical sodium-dependent bile acid transporter is a risk factor for gallstone disease.

PloS one - 13 Oct 2009

Renner Olga, Harsch Simone, Schaeffeler Elke, Winter Stefan, Schwab Matthias, Krawczyk Marcin, Rosendahl Jonas, Wittenburg Henning, Lammert Frank, Stange Eduard F

Abstract excerpt

BACKGROUND: Cholelithiasis is a multifactorial process and several mechanisms of gallstone formation have been postulated. As one of these mechanisms, a decreased expression of the ileal apical sodium-dependent bile acid transporter gene SLC10A2 in gallstone carriers was described previously. In this study the SLC10A2 gene was investigated to identify novel genetic variants and their association with gallstone...

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PMID: 19823678
DOI: 10.1371/journal.pone.0007321
PMCID: PMC2757911

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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