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Intrahost Genetic Diversity of Dengue Virus in Human Hosts and Mosquito Vectors under Natural Conditions Which Impact Replicative Fitness In Vitro.

Viruses - 17 Apr 2023

Nonyong Patcharaporn, Ekalaksananan Tipaya, Phanthanawiboon Supranee, Overgaard Hans J, Alexander Neal, Thaewnongiew Kesorn, Sawaswong Vorthon, Nimsamer Pattaraporn, Payungporn Sunchai, Phadungsombat Juthamas, Nakayama Emi E, Shioda Tatsuo, Pientong Chamsai

Abstract excerpt

Dengue virus (DENV) is an arbovirus whose transmission cycle involves disparate hosts: humans and mosquitoes. The error-prone nature of viral RNA replication drives the high mutation rates, and the consequently high genetic diversity affects viral fitness over this transmission cycle. A few studies have been performed to investigate the intrahost genetic diversity between hosts, although their mosquito infections...

Topics

Animals
Humans
Dengue Virus
Dengue
Mosquito Vectors
Aedes
Genetic Variation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 37112962
DOI: 10.3390/v15040982
PMCID: PMC10143933

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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