Quantitative measures of within-host viral genetic diversity.

doi:10.1016/j.coviro.2021.06.002

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Article

Quantitative measures of within-host viral genetic diversity.

Current opinion in virology - 1 Aug 2021

Fuhrmann Lara, Jablonski Kim Philipp, Beerenwinkel Niko

Abstract excerpt

The genetic diversity of virus populations within their hosts is known to influence disease progression, treatment outcome, drug resistance, cell tropism, and transmission risk, and the study of dynamic changes of genetic heterogeneity can provide insights into the evolution of viruses. Several measures to quantify within-host genetic diversity capturing different aspects of diversity patterns in a sample or...

Topics

Genetic Variation
Genome, Viral
Haplotypes
Humans
Mutation
Phylogeny
Quasispecies
Virus Diseases
Viruses

Source

Open in PubMed

Identifiers

PMID: 34153841
DOI: 10.1016/j.coviro.2021.06.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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