Dengue Virus Serotype 2 Intrahost Diversity in Patients with Different Clinical Outcomes.

doi:10.3390/v13020349

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Article

Dengue Virus Serotype 2 Intrahost Diversity in Patients with Different Clinical Outcomes.

Viruses - 23 Feb 2021

Torres Maria Celeste, Lima de Mendonça Marcos Cesar, Damasceno Dos Santos Rodrigues Cintia, Fonseca Vagner, Ribeiro Mario Sergio, Brandão Ana Paula, Venâncio da Cunha Rivaldo, Dias Ana Isabel, Santos Vilas Boas Lucy, Felix Alvina Clara, Alves Pereira Maira, de Oliveira Pinto Luzia Maria, Sakuntabhai Anavaj, Bispo de Filippis Ana Maria, On Behalf Of ZikAction Consortium

Abstract excerpt

Intrahost genetic diversity is thought to facilitate arbovirus adaptation to changing environments and hosts, and it might also be linked to viral pathogenesis. Dengue virus serotype 2 (DENV-2) has circulated in Brazil since 1990 and is associated with severe disease and explosive outbreaks. Intending to shed light on the viral determinants for severe dengue pathogenesis, we sought to analyze the DENV-2 intrahost...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Brazil
Child
Child, Preschool
Dengue
Dengue Virus
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Variation

Genome, Viral

Humans

Infant

Male

Middle Aged

Phylogeny

Serogroup

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PMID: 33672226
DOI: 10.3390/v13020349
PMCID: PMC7926750

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