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Article

Tracking Dengue Virus Intra-host Genetic Diversity during Human-to-Mosquito Transmission.

PLoS neglected tropical diseases - 1 Jan 2015

Sim Shuzhen, Aw Pauline P K, Wilm Andreas, Teoh Garrett, Hue Kien Duong Thi, Nguyen Nguyet Minh, Nagarajan Niranjan, Simmons Cameron P, Hibberd Martin L

Abstract excerpt

Dengue virus (DENV) infection of an individual human or mosquito host produces a dynamic population of closely-related sequences. This intra-host genetic diversity is thought to offer an advantage for arboviruses to adapt as they cycle between two very different host species, but it remains poorly characterized. To track changes in viral intra-host genetic diversity during horizontal transmission, we infected...

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Identifiers

PMID: 26325059
DOI: 10.1371/journal.pntd.0004052
PMCID: PMC4556672

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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