Article
The role of brain-derived neurotrophic factor (BDNF) Val66Met genetic polymorphism in bipolar disorder: a case-control study, comorbidities, and meta-analysis of 16,786 subjects.
Bipolar disorders - 1 Feb 2015
González-Castro Thelma Beatriz, Nicolini Humberto, Lanzagorta Nuria, López-Narváez Lilia, Genis Alma, Pool García Sherezada, Tovilla-Zárate Carlos Alfonso
Abstract excerpt
OBJECTIVES: The aim of this study was to evaluate the association of Val66Met brain-derived neurotrophic factor (BDNF) polymorphism with bipolar disorder in (i) a meta-analysis and (ii) a case-control study in a Mexican population. We also investigated the possible association of this polymorphism with clinical features. METHODS: We performed a keyword search of the PubMed and Web of Science databases. A total of...
Topics
- Adult
- Bipolar Disorder
- Brain-Derived Neurotrophic Factor
- Case-Control Studies
- Dipeptides
- Female
- Genotype
- Humans
- Male
- Mexico