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Article

Association of brain-derived neurotrophic factor (BDNF) Val66Met polymorphism with early-onset bipolar disorder.

Bipolar disorders - 1 Sept 2015

Nassan Malik, Croarkin Paul E, Luby Joan L, Veldic Marin, Joshi Paramjit T, McElroy Susan L, Post Robert M, Walkup John T, Cercy Kelly, Geske Jennifer R, Wagner Karen D, Cuellar-Barboza Alfredo B, Casuto Leah, Lavebratt Catharina, Schalling Martin, Jensen Peter S, Biernacka Joanna M, Frye Mark A

Abstract excerpt

OBJECTIVES: Brain-derived neurotrophic factor (BDNF) Val66Met (rs6265) functional polymorphism has been implicated in early-onset bipolar disorder. However, results of studies are inconsistent. We aimed to further explore this association. METHODS: DNA samples from the Treatment of Early Age Mania (TEAM) and Mayo Clinic Bipolar Disorder Biobank were investigated for association of rs6265 with early-onset bipolar...

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Source

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Identifiers

PMID: 26528762
DOI: 10.1111/bdi.12323
PMCID: PMC4672380

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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