Association between brain-derived neurotrophic factor genetic polymorphism Val66Met and susceptibility to bipolar disorder: a meta-analysis.

doi:10.1186/s12888-014-0366-9

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Back to search

Article

Association between brain-derived neurotrophic factor genetic polymorphism Val66Met and susceptibility to bipolar disorder: a meta-analysis.

BMC psychiatry - 24 Dec 2014

Wang Zuowei, Li Zezhi, Gao Keming, Fang Yiru

Abstract excerpt

BACKGROUND: In view of previous conflicting findings, this meta-analysis was performed to comprehensively determine the overall strength of associations between brain-derived neurotrophic factor (BDNF) genetic polymorphism Val66Met and susceptibility to bipolar disorders (BPD). METHODS: Literatures published and cited in Pubmed and Wanfang Data was searched with terms of 'Val66Met', 'G196A', 'rs6265', 'BDNF',...

Topics

Alleles
Amino Acid Substitution
Asian People
Bipolar Disorder
Brain-Derived Neurotrophic Factor
Case-Control Studies
Female
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genotype

Humans

Methionine

Polymorphism, Genetic

Valine

White People

Source

Open in PubMed Open full text

Identifiers

PMID: 25539739
DOI: 10.1186/s12888-014-0366-9
PMCID: PMC4297385

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between brain-derived neurotrophic factor genetic polymorphism Val66Met and susceptibility to bipolar disorder: a meta-analysis.PMID 25539739Read ↗

Brain derived neurotrophic factor (BDNF) Val66Met polymorphism is not risk factor for bipolar disorderSemantic proximity Read ↗

The role of brain-derived neurotrophic factor (BDNF) Val66Met genetic polymorphism in bipolar disorder: a case-control study, comorbidities, and meta-analysis of 16,786 subjects.Semantic proximity Read ↗

Meta-analysis reveals no association of the Val66Met polymorphism of brain-derived neurotrophic factor with either schizophrenia or bipolar disorder.Semantic proximity Read ↗

Genetics of bipolar disorder: focus on BDNF Val66Met polymorphism.Semantic proximity Read ↗

BDNF Val66Met polymorphism and bipolar disorder in European populations: A risk association in case-control, family-based and GWAS studies.Semantic proximity Read ↗

Positive association between the brain-derived neurotrophic factor (BDNF) gene and bipolar disorder in the Han Chinese population.Semantic proximity Read ↗

Association of BDNF gene polymorphism with bipolar disorders in Han Chinese population.Semantic proximity Read ↗

Brain-Derived Neurotrophic Factor Gene Val66Met Polymorphism and Risk of Schizophrenia: A Meta-analysis of Case-Control Studies.Semantic proximity Read ↗

No association between the Val66Met polymorphism of the brain-derived neurotrophic factor gene and bipolar disorder in a Japanese population: a multicenter study.Semantic proximity Read ↗

Confirmation of association between the Val66Met polymorphism in the brain-derived neurotrophic factor (BDNF) gene and bipolar I disorder.Semantic proximity Read ↗

Brain-derived neurotrophic factor Val66Met and psychiatric disorders: meta-analysis of case-control studies confirm association to substance-related disorders, eating disorders, and schizophrenia.Semantic proximity Read ↗

Association study of the brain-derived neurotrophic factor (BDNF) gene with bipolar disorder.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.