Article
Brain-derived neurotrophic factor as a potential risk locus for bipolar disorder: evidence, limitations, and implications.
Current psychiatry reports - 1 Dec 2003
Green Elaine, Craddock Nick
Abstract excerpt
Brain-derived neurotrophic factor (BDNF) plays an important role in promoting and modifying growth, development, and survival of neuronal populations, and, in the mature nervous system, is involved in activity-dependent neuronal plasticity. Based on several lines of evidence, BDNF has been hypothesized to play an important role in the pathogenesis of mood disorder and the therapeutic action of at least some...
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