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Article

Mutational analysis of tumour suppressor gene NF2 in common solid cancers and acute leukaemias.

Pathology - 1 Jan 2012

Yoo Nam Jin, Park Sang Wook, Lee Sug Hyung

Abstract excerpt

AIMS: Germline mutation of NF2 gene is a feature of neurofibromatosis type 2 familial cancer syndrome. Also, somatic point mutations of NF2 mutation have been reported in tumours originated from nerve structures. A recent study revealed that NF2 gene was mutated in renal cell carcinoma (RCC) as well, suggesting a possibility that NF2 gene might be somatically mutated in other human cancers. The aim of this study...

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Share to Carcinoma, Hepatocellular
Share to DNA, Neoplasm
Share to Genes, Neurofibromatosis 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukemia, Myeloid, Acute

Share to Polymorphism, Single-Stranded Conformational

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

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Source

Identifiers

PMID: 22081132
DOI: 10.1097/PAT.0b013e32834c3599

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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