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Article

DNA-binding small-ligand-immobilized surface plasmon resonance biosensor for detecting thymine-related single-nucleotide polymorphisms.

Chemistry (Weinheim an der Bergstrasse, Germany) - 9 Dec 2011

Miura Sara, Nishizawa Seiichi, Suzuki Akinori, Fujimoto Yukiko, Ono Katsuya, Gao Qiang, Teramae Norio

Abstract excerpt

A surface plasmon resonance (SPR) biosensor that carries DNA-binding small ligands has been developed for the detection of single-nucleotide polymorphisms (SNPs). 3,5-Diaminopyrazine derivatives, with a hydrogen-bonding profile fully complementary to the thymine base, were utilized as recognition elements on the sensor surface, and a target single-stranded DNA sequence was hybridized with a DNA probe containing...

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Source

Identifiers

PMID: 22076973
DOI: 10.1002/chem.201101290

Genes

SPR
CAT
CGA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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