Article
Kinetic discrimination of DNA single-base mutations by localized surface plasmon resonance.
Journal of colloid and interface science - 1 Feb 2017
Rapisarda Antonino, Giamblanco Nicoletta, Marletta Giovanni
Abstract excerpt
Clinical application of DNA microarrays used for screening of single nucleotide polymorphisms (SNPs) are very important for diagnosis of diseases and appropriate treatment of patients. In this paper localized surface plasmon resonance (LSPR) technique has been used to study the DNA hybridization process for binary solutions of respectively perfectly matching (PM) and single base mismatching (MM) 93-mer ssDNA from...
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