Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A surface plasmon resonance sensor based on 3,5-diaminopyrazine with a high selectivity for thymine in AP site-containing DNA duplex.

Nucleic acids symposium series (2004) - 1 Jan 2008

Miura Sara, Ono Katsuya, Watanabe Miwa, Nishizawa Seiichi, Teramae Norio

Abstract excerpt

We here report on a surface plasmon resonance (SPR) sensor carrying small organic ligands for the detection of single-nucleotide polymorphisms (SNPs). Two kinds of ligands are prepared, both of which have a hydrogen-bond forming site suitable for nucleobase recognition, and have an active amino group for the immobilization to the sensor chip. While the sensor immobilized flavin does not show any useful responses,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA
Share to DNA Probes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ligands

Share to Polymorphism, Single Nucleotide

Share to Pyrazines

Share to Pyrimidinones

Share to Surface Plasmon Resonance

Share to Thymine

Source

Identifiers

PMID: 18776284
DOI: 10.1093/nass/nrn063

Genes

SPR
CAT
CGA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A surface plasmon resonance sensor based on 3,5-diaminopyrazine with a high selectivity for thymine in AP site-containing DNA duplex.PMID 18776284Read ↗

DNA-binding small-ligand-immobilized surface plasmon resonance biosensor for detecting thymine-related single-nucleotide polymorphisms.Semantic proximity Read ↗

Fluorescence detection of thymidine-related single-nucleotide polymorphisms by 3, 5-diaminopyrazine derivatives.Semantic proximity Read ↗

Recent progress in abasic site-binding small molecules for detecting single-base mutations in DNA.Semantic proximity Read ↗

Bioanalytical approaches for the detection of single nucleotide polymorphisms by Surface Plasmon Resonance biosensors.Semantic proximity Read ↗

Use of abasic site-containing DNA for electrochemical SNPs detection.Semantic proximity Read ↗

Fluorescence light-up recognition of DNA nucleotide based on selective abasic site binding of an excited-state intramolecular proton transfer probe.Semantic proximity Read ↗

Gold-nanorod-based colorimetric and fluorescent approach for sensitive and specific assay of disease-related gene and mutation.Semantic proximity Read ↗

NBD-based green fluorescent ligands for typing of thymine-related SNPs by using an abasic site-containing probe DNA.Semantic proximity Read ↗

Hydrogen bond-mediated binding of ligands to a nucleobase at a gap site in a DNA duplex and its use for fluorescence detection of single-nucleotide polymorphisms.Semantic proximity Read ↗

Peptide nucleic acid-assisted colorimetric detection of single-nucleotide polymorphisms based on the intrinsic peroxidase-like activity of hemin-carbon nanotube nanocomposites.Semantic proximity Read ↗

Electrochemical coding of single-nucleotide polymorphisms by monobase-modified gold nanoparticles.Semantic proximity Read ↗

Fluorescence detection of single nucleotide polymorphisms using a universal molecular beacon.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.