Article
Streptavidin-enhanced assay for sensitive and specific detection of single nucleotide polymorphism in TP53.
Analytical and bioanalytical chemistry - 1 Mar 2011
Sípová Hana, Springer Tomáš, Homola Jiří
Abstract excerpt
This paper reports an approach to detection of single nucleotide polymorphism based on special amplification assay and surface plasmon resonance biosensor technology. In this assay, a part of the target DNA is recognized by a probe (probe A) coupled with streptavidin-oligonucleotide (SON) complexes ex situ, and when the mixture is injected in the sensor, another part of the target DNA is recognized by a DNA probe...
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