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Article

Differential pathotropism of non-immortalized and immortalized human neural stem cell lines in a focal demyelination model.

Cellular and molecular life sciences : CMLS - 1 Apr 2012

Ferrari Daniela, Zalfa Cristina, Nodari Laura Rota, Gelati Maurizio, Carlessi Luigi, Delia Domenico, Vescovi Angelo Luigi, De Filippis Lidia

Abstract excerpt

Cell therapy is reaching the stage of phase I clinical trials for post-traumatic, post-ischemic, or neurodegenerative disorders, and the selection of the appropriate cell source is essential. In order to assess the capacity of different human neural stem cell lines (hNSC) to contribute to neural tissue regeneration and to reduce the local inflammation after an acute injury, we transplanted GMP-grade...

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Identifiers

PMID: 22076651
DOI: 10.1007/s00018-011-0873-5
PMCID: PMC11115189

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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