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Article

Inhibition of HCV 3a genotype entry through host CD81 and HCV E2 antibodies.

Journal of translational medicine - 10 Nov 2011

Ashfaq Usman A, Qasim Muhammad, Yousaf Muhammad Z, Awan Muhammad Tariq, Jahan Shah

Abstract excerpt

BACKGROUND: HCV causes acute and chronic hepatitis which can eventually lead to permanent liver damage hepatocellular carcinoma and death. HCV glycoproteins play an important role in HCV entry by binding with CD81 receptors. Hence inhibition of virus at entry step is an important target to identify antiviral drugs against HCV. METHODS AND RESULT: The present study elaborated the role of CD81 and HCV glycoprotein...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22074322
DOI: 10.1186/1479-5876-9-194
PMCID: PMC3228851

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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