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Optimized cell systems for the investigation of hepatitis C virus E1E2 glycoproteins

4 Nov 2020

Abstract excerpt

Great strides have been made in understanding and treating hepatitis C virus (HCV) thanks to the development of various experimental systems including cell-culture-proficient HCV, the HCV pseudoparticle system and soluble envelope glycoproteins. The HCV pseudoparticle (HCVpp) system is a platform used extensively in studies of cell entry, screening of novel entry inhibitors, assessing the phenotypes of clinically...

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PMID: 33147126
DOI: 10.1099/jgv.0.001512

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