Genetic variation in the NBS1 gene is associated with hepatic cancer risk in a Chinese population.

doi:10.1089/dna.2011.1421

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Genetic variation in the NBS1 gene is associated with hepatic cancer risk in a Chinese population.

DNA and cell biology - 1 May 2012

Huang Ming-De, Chen Xiao-Fei, Xu Gang, Wu Qing-Quan, Zhang Jian-Huai, Chen Guo-Feng, Cai Yong, Qi Fu-Zhen

Abstract excerpt

NBS1 plays important roles in maintaining genomic stability as a key DNA repair protein in the homologous recombination repair pathway and as a signal modifier in the intra-S phase checkpoint. We hypothesized that polymorphisms of NBS1 are associated with hepatic cancer (HCC) risk. The NBS1 rs1805794 C/G polymorphism has been frequently studied in some cancers with discordant results, but its association with HCC...

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PMID: 22070649
DOI: 10.1089/dna.2011.1421
PMCID: PMC3358090

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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