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Article

Disease-Associated Risk Variants and Expression Levels of the lncRNA, CDKN2B-AS1, Are Associated With the Progression of HCC.

Journal of cellular and molecular medicine - 1 Mar 2025

Hsueh Kuan-Chun, Lee Hsiang-Lin, Ho Kuo-Hao, Chang Lun-Ching, Yang Shun-Fa, Chien Ming-Hsien

Abstract excerpt

The most susceptible loci of hepatocellular carcinoma (HCC) identified by genome-wide association studies are located in non-coding regions. The antisense non-coding RNA at the INK4 locus (ANRIL), also known as cyclin-dependent kinase inhibitor 2B antisense RNA 1 (CDKN2B-AS1), is a long non-coding (lnc)RNA situated within and antisense to genes encoding CDKN2A/B on chromosome 9p21.3. Single-nucleotide...

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Source

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Identifiers

PMID: 40105653
DOI: 10.1111/jcmm.70496
PMCID: PMC11921468

Genes

CDKN2B
CDKN2A

Provenance

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