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Article

Cyclin D1 G870A polymorphism and the risk of hepatocellular carcinoma in a Chinese population.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jun 2014

Hu Zhangyong, Zhou Zhipeng, Xiong Guolian, Wang Yali, Lai Yi, Deng Lan, Yang Jinliang

Abstract excerpt

Cyclin D1, encoded by the gene CCND1, is a regulatory protein in the cell cycle transition from G1 phase to S phase. A common polymorphism (G870A) in the exon 4 of CCND1 gene affects splicing of the CCND1 transcript and may cause uncontrollable cellular growth. Therefore, the CCND1 G870A polymorphism may influence an individual's susceptibility to the development of certain tumors. The present study was performed...

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Source

Identifiers

PMID: 24570185
DOI: 10.1007/s13277-014-1741-3

Genes

CCND1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Cyclin D1 G870A polymorphism and the risk of hepatocellular carcinoma in a Chinese population.PMID 24570185Read ↗

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